Nucleic acid probes


Nucleic acid probes are used not only to detect mRNA, but to assess interphase chromosomes in tumor cells. Probe is placed into contact with the sample under conditions that allow the probe sequence to hybridize with its complementary sequence. Probes may consist of either DNA or RNA, and they vary in length from short oligonucleotides to mutagenic chromosomal segments cloned into bacteria.



 



 


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